2. Proximal convoluted tubule

This epithelial tube begins at the urinary pole of the rcnal corpuscle. Its lining is simple low columnar-to-cuboidal epithelium. The lining cells have abundant long microvilli. Together they form a brush border that partly obscures the lumen and increases the surface area available for absorption. The convoluted part of the proximal tubule lies in the cortex and empties into its straight portion (also called the thick descending limb of the loop of Henle), which has a similar epithelium and function. Together, the convoluted and straight portions of the proximal tubule measure about 14 mm, making this the longest portion of the nephron.

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