Filtration

  • Renal filtrate 
  • plasma minus blood cells and blood proteins
  • most reabsorbed (99%)
  • Filtration membrane: fenestrated endothelium, basement membrane and pores formed by podocytes
  • Filtration pressure : responsibl for filtrate formation
  • Glomerular capillary pressure (GCP) minus capsule pressure (CP) minua colloid osmotic pressure (COP)
  • Changes caused by glomerular capillary pressure
  • Glomerular filtrate, glomerular filtration rate (GFR)
  • GFR=180 lt/day
  • Inulin is used to calculate GFR
  • Inulin can not be reabsorbed or secreted from tubules after filtration
  • Urine and plasma amount of inulin are measured after it is given intraenously.

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